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Malaria is an infectious disease caused by a parasite that can be transmitted to humans through the bites of an infected mosquito. People with malaria usually feel very sick and have a high fever with shaking chills. Chloroquine or hydroxychloroquine is often advised to prevent and treat malaria. Other drugs that treat malaria include artemether-lumefantrine, doxycycline, Malarone, mefloquine, primaquine, etc.